I had the opposite situation, Caucasian family, both young first time parents. Baby looked so abnormal to me and quite a few nurses too. Very slanted almond eyes, tongue protruding, ears sort of low set and pinky fingers turned somewhat. I was about 80% sure she was Down's. Went in and looked at the parents and neither of them looked like her really AND I found out that mom had a scare because her AFP had been low but repeated as WNL. So I made the speech, did the test, had them in tears and scared out of their minds. A week later the test was neg. Parents were relieved but a bit miffed at me putting them through it. I felt so bad, I was so sure that she was going to be Down's. Now at 6 months she looks NOTHING like how she did before and has not the slightest Down's features. Oh well, I had to, I would have felt worse telling them after 4 months that she had Down's but I didn't have the guts to diagnose it . Dianna Tolen, M.D. Kids First Pediatric Care Canfield, Ohio